On the Intelligent Finance website
http://www.if.com/savings/minicashisa.asp it suggests that if you have an offset mortgage you could offset your mini ISA against it, to reduce the repayment period.
Err.. I thought an ISA was tax-free. If so, wouldn't you be wasting the tax-free benefit by off-setting it against your mortgage? I can see there might not be much net difference, since the mortgage interest rate is much better than the saving interest rates in general, and the latter gets taxed, but say you had two lots of £3k to save. The ISA should be separate from the mortgage, surely, to benefit from the tax exemption.